Seasonal Influenza Split Vaccines Confer Partial Cross-Protection against Heterologous Influenza Virus in Ferrets When Combined with the CAF01 Adjuvant

Seasonal Influenza Split Vaccines Confer Partial Cross-Protection against Heterologous Influenza Virus in Ferrets When Combined with the CAF01 Adjuvant

Influenza epidemics occur annually, and estimated 5–10% of the adult population and 20–30% of children will become ill from influenza infection. Seasonal vaccines primarily work through the induction of neutralizing antibodies against the principal surface antigen hemagglutinin (HA). This important...

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Bibliographic Details
Main Authors: Dennis Christensen, Jan P. Christensen, Karen S. Korsholm, Louise K. Isling, Karin Erneholm, Allan R. Thomsen, Peter Andersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
influenza A virus
adjuvants
immunologic
heterologous immunity
ferrets
T cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01928/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01928/full

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