Expanding the Host Range of Hepatitis C Virus through Viral Adaptation

Expanding the Host Range of Hepatitis C Virus through Viral Adaptation

Hepatitis C virus (HCV) species tropism is incompletely understood. We have previously shown that at the level of entry, human CD81 and occludin (OCLN) comprise the minimal set of human factors needed for viral uptake into murine cells. As an alternative approach to genetic humanization, species bar...

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Bibliographic Details
Main Authors: Markus von Schaewen, Marcus Dorner, Kathrin Hueging, Lander Foquet, Sherif Gerges, Gabriela Hrebikova, Brigitte Heller, Julia Bitzegeio, Juliane Doerrbecker, Joshua A. Horwitz, Gisa Gerold, Sebastian Suerbaum, Charles M. Rice, Philip Meuleman, Thomas Pietschmann, Alexander Ploss
Format: Article
Language:English
Published: American Society for Microbiology 2016-11-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/6/e01915-16

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http://mbio.asm.org/cgi/content/full/7/6/e01915-16

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