Soluble isoforms of vascular endothelial growth factor are predictors of response to sunitinib in metastatic renal cell carcinomas.

Soluble isoforms of vascular endothelial growth factor are predictors of response to sunitinib in metastatic renal cell carcinomas.

Angiogenesis is the target of several agents in the treatment of malignancies, including renal cell carcinoma (RCC). There is a real need for surrogate biomarkers that can predict selection of patients who may benefit from antiangiogenic therapies, prediction of disease outcome and which may improve...

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Main Authors: Bernard Paule, Laurence Bastien, Emmanuelle Deslandes, Olivier Cussenot, Marie-Pierre Podgorniak, Yves Allory, Benyoussef Naïmi, Raphael Porcher, Alexandre de La Taille, Suzanne Menashi, Fabien Calvo, Samia Mourah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2873294?pdf=render

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http://europepmc.org/articles/PMC2873294?pdf=render

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