In Vitro Assessment of Cytochrome P450 2C19 Potential of Naoxintong

The effects of Buchang Naoxintong Capsules (BNCs) on S-mephenytoin 4′-hydroxylation activities in human liver microsomes in vitro were assessed. Human liver microsome was prepared by different ultracentrifugation. Human liver microsome incubation experiment was carried out to assay BNC on S-mephenyt...

Full description

Bibliographic Details
Main Authors: Hui Chen, Ya Zhang, Xiaoying Wu, Candong Li, Huan Wang
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2012/430262