Activation of BMP-Smad1/5/8 signaling promotes survival of retinal ganglion cells after damage in vivo.

While the essential role of bone morphogenetic protein (BMP) signaling in nervous system development is well established, its function in the adult CNS is poorly understood. We investigated the role of BMP signaling in the adult mouse retina following damage in vivo. Intravitreal injection of N-meth...

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Bibliographic Details
Main Authors: Yumi Ueki, Thomas A Reh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3368846?pdf=render