Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease
Mitochondrial Ca2+ uptake plays a pivotal role both in cell energy balance and in cell fate determination. Studies on the role of mitochondrial Ca2+ signaling in pathophysiology have been favored by the identification of the genes encoding the mitochondrial calcium uniporter (MCU) and its regulatory...
Main Authors: | Cristina Mammucari, Gaia Gherardi, Rosario Rizzuto |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-07-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fonc.2017.00139/full |
Similar Items
-
The Mitochondrial Ca2+ Uptake and the Fine-Tuning of Aerobic Metabolism
by: Gaia Gherardi, et al.
Published: (2020-10-01) -
Different Sensitivity of Control and MICU1- and MICU2-Ablated <i>Trypanosoma cruzi</i> Mitochondrial Calcium Uniporter Complex to Ruthenium-Based Inhibitors
by: Mayara S. Bertolini, et al.
Published: (2020-12-01) -
The Mitochondrial Calcium Uniporter Interacts with Subunit c of the ATP Synthase of Trypanosomes and Humans
by: Guozhong Huang, et al.
Published: (2020-03-01) -
Mitochondrial calcium regulation during and following contractions in skeletal muscle
by: Hiroaki Eshima, et al.
Published: (2018-07-01) -
The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle
by: Carlos Manlio Díaz-García, et al.
Published: (2021-02-01)