Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis

Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis

Abstract Background Neoplastic invasion into leptomeninges and subarachnoid space, resulting in neoplastic meningitis (NM) is a fatal complication of advanced solid and hematological neoplasms. Identification of malignant involvement of the cerebrospinal fluid (CSF) early in the disease course has c...

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Bibliographic Details
Main Authors: Catharina Conrad, Kristina Dorzweiler, Miles A. Miller, Douglas A. Lauffenburger, Herwig Strik, Jörg W. Bartsch
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Fluids and Barriers of the CNS
Subjects:
Neoplastic meningitis
Metalloproteases
CSF
Real-time protease activities
FRET-substrates
Online Access:http://link.springer.com/article/10.1186/s12987-017-0070-5

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http://link.springer.com/article/10.1186/s12987-017-0070-5

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