Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage.

Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage.

Matrix metalloproteinases-2 and -9 (MMP-2/-9) are key tissue remodeling enzymes that have multiple overlapping activities critical for wound healing and tumor progression in vivo. To overcome issues of redundancy in studying their functions in vivo, we created MMP-2/-9 double knockout (DKO) mice in...

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Bibliographic Details
Main Authors: Dina V Hingorani, Csilla N Lippert, Jessica L Crisp, Elamprakash N Savariar, Jonathan P C Hasselmann, Christopher Kuo, Quyen T Nguyen, Roger Y Tsien, Michael A Whitney, Lesley G Ellies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6152858?pdf=render

Internet

http://europepmc.org/articles/PMC6152858?pdf=render

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