Field-evaluation of a new lateral flow assay for detection of cellular and humoral immunity against Mycobacterium leprae.

BACKGROUND:Field-applicable tests detecting asymptomatic Mycobacterium leprae (M. leprae) infection or predicting progression to leprosy, are urgently required. Since the outcome of M. leprae infection is determined by cellular- and humoral immunity, we aim to develop diagnostic tests detecting pro-...

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Bibliographic Details
Main Authors: Kidist Bobosha, Elisa M Tjon Kon Fat, Susan J F van den Eeden, Yonas Bekele, Jolien J van der Ploeg-van Schip, Claudia J de Dood, Karin Dijkman, Kees L M C Franken, Louis Wilson, Abraham Aseffa, John S Spencer, Tom H M Ottenhoff, Paul L A M Corstjens, Annemieke Geluk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4014418?pdf=render