HID-1 is required for homotypic fusion of immature secretory granules during maturation

HID-1 is required for homotypic fusion of immature secretory granules during maturation

Secretory granules, also known as dense core vesicles, are generated at the trans-Golgi network and undergo several maturation steps, including homotypic fusion of immature secretory granules (ISGs) and processing of prehormones to yield active peptides. The molecular mechanisms governing secretory...

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Bibliographic Details
Main Authors: Wen Du, Maoge Zhou, Wei Zhao, Dongwan Cheng, Lifen Wang, Jingze Lu, Eli Song, Wei Feng, Yanhong Xue, Pingyong Xu, Tao Xu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-10-01
Series:eLife
Subjects:
HID-1
homotypic fusion
secretory granules maturation
FIB/SEM
Online Access:https://elifesciences.org/articles/18134

Internet

https://elifesciences.org/articles/18134

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