Failure of intrathecal allogeneic mesenchymal stem cells to halt progressive demyelination in two boys with cerebral adrenoleukodystrophy

Failure of intrathecal allogeneic mesenchymal stem cells to halt progressive demyelination in two boys with cerebral adrenoleukodystrophy

Abstract Cerebral adrenoleukodystrophy is an inflammatory demyelinating condition that is the result of a mutation in the X‐linked ABCD1 gene, a peroxisomal very long chain fatty acid transporter. Although mutations in this gene result in adrenal insufficiency in the majority of affected individuals...

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Bibliographic Details
Main Authors: Ashish Gupta, Paul J. Orchard, Weston P. Miller, Dave R. Nascene, Gerald V. Raymond, Daniel J. Loes, David H. McKenna, Troy C. Lund
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Stem Cells Translational Medicine
Subjects:
adrenoleukodystrophy
autoimmune
demyelination
inflammation
mesenchymal stem cells
Online Access:https://doi.org/10.1002/sctm.19-0304

Internet

https://doi.org/10.1002/sctm.19-0304

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