Obstacles to detecting isoforms using full-length scRNA-seq data
Abstract Background Early single-cell RNA-seq (scRNA-seq) studies suggested that it was unusual to see more than one isoform being produced from a gene in a single cell, even when multiple isoforms were detected in matched bulk RNA-seq samples. However, these studies generally did not consider the i...
Main Authors: | Jennifer Westoby, Pavel Artemov, Martin Hemberg, Anne Ferguson-Smith |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13059-020-01981-w |
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