Identification of a highly antigenic linear B cell epitope within Plasmodium vivax apical membrane antigen 1 (AMA-1).

Apical membrane antigen 1 (AMA-1) is considered to be a major candidate antigen for a malaria vaccine. Previous immunoepidemiological studies of naturally acquired immunity to Plasmodium vivax AMA-1 (PvAMA-1) have shown a higher prevalence of specific antibodies to domain II (DII) of AMA-1. In the p...

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Main Authors: Lilian Lacerda Bueno, Francisco Pereira Lobo, Cristiane Guimarães Morais, Luíza Carvalho Mourão, Ricardo Andrez Machado de Ávila, Irene Silva Soares, Cor Jesus Fontes, Marcus Vinícius Lacerda, Carlos Chavez Olórtegui, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara, Erika Martins Braga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3119695?pdf=render