Single-Cell RNA-Seq Uncovers a Robust Transcriptional Response to Morphine by Glia

Summary: Molecular and behavioral responses to opioids are thought to be primarily mediated by neurons, although there is accumulating evidence that other cell types play a prominent role in drug addiction. To investigate cell-type-specific opioid responses, we performed single-cell RNA sequencing (...

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Bibliographic Details
Main Authors: Denis Avey, Sumithra Sankararaman, Aldrin K.Y. Yim, Ruteja Barve, Jeffrey Milbrandt, Robi D. Mitra
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718313846