Suppressor of variegation 3–9 homologue 1 impairment and neutrophil-skewed systemic inflammation are associated with comorbidities in COPD

Abstract Background Systemic manifestations and comorbidities are characteristics of chronic obstructive pulmonary disease (COPD) and are probably due to systemic inflammation. The histone methyltransferase SUV39H1 controls the Th1/Th2 balance. We previously reported that reduced SUV39H1 expression...

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Main Authors: Tzu-Tao Chen, Sheng-Ming Wu, Kuan-Yuan Chen, Chien-Hua Tseng, Shu-Chuan Ho, Hsiao-Chi Chuang, Po-Hao Feng, Wen-Te Liu, Chia-Li Han, Erick Wan-Chun Huang, Yun-Kai Yeh, Kang-Yun Lee
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-021-01628-x