Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept

Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept

Abstract Background In light of the vulnerability of the developing brain, mixture risk assessment (MRA) for the evaluation of developmental neurotoxicity (DNT) should be implemented, since infants and children are co-exposed to more than one chemical at a time. One possible approach to tackle MRA c...

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Bibliographic Details
Main Authors: Francesca Pistollato, Emilio Mendoza de Gyves, Donatella Carpi, Stephanie K. Bopp, Carolina Nunes, Andrew Worth, Anna Bal-Price
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Environmental Health
Subjects:
Mixture risk assessment
Adverse outcome pathway
Human induced pluripotent stem cells
Neuronal differentiation
Children health
Online Access:http://link.springer.com/article/10.1186/s12940-020-00578-x

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http://link.springer.com/article/10.1186/s12940-020-00578-x

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