Improvement of High Affinity and Selectivity on Biosensors Using Genetically Engineered Phage by Binding Isotherm Screening

Improvement of High Affinity and Selectivity on Biosensors Using Genetically Engineered Phage by Binding Isotherm Screening

The genetically engineered M13 bacteriophage (M13 phage), developed via directed evolutionary screening process, can improve the sensitivity of sensors because of its selective binding to a target material. Herein, we propose a screening method to develop a selective and sensitive bioreporter for to...

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Bibliographic Details
Main Authors: Jong-Min Lee, Eun Jung Choi, Juyun Park, Vasanthan Devaraj, ChunTae Kim, Jiye Han, Won-Geun Kim, Kyujung Kim, Yong-Cheol Kang, Kwang Ho Kim, Jin-Woo Oh
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
M13 bacteriophage
directed evolution
binding affinity
surface-enhanced Raman scattering
Online Access:http://www.mdpi.com/1999-4915/11/3/248

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http://www.mdpi.com/1999-4915/11/3/248

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