An implantable human stem cell-derived tissue-engineered rostral migratory stream for directed neuronal replacement

O’Donnell et al. describe their Tissue-Engineered Rostral Migratory Stream (TE-RMS) comprised of human astrocyte-like cells that can be derived from adult gingival stem cells within one week, which reorganizes into bundles of bidirectional, longitudinally-aligned astrocytes to emulate the endogenous...

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Bibliographic Details
Main Authors: John C. O’Donnell, Erin M. Purvis, Kaila V. T. Helm, Dayo O. Adewole, Qunzhou Zhang, Anh D. Le, D. Kacy Cullen
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02392-8