Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma
In 1982, the term “prions” (proteinaceous infectious particles) was coined to specify a new principle of infection. A misfolded isoform of a cellular protein has been described as the causative agent of a fatal neurodegenerative disease. At the beginning of prion research scientists assumed that the...
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-01-01
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| Series: | Biology |
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| Online Access: | http://www.mdpi.com/2079-7737/5/1/2 |