On the epigenetic role of guanosine oxidation

Chemical modifications of DNA and RNA regulate genome functions or trigger mutagenesis resulting in aging or cancer. Oxidations of macromolecules, including DNA, are common reactions in biological systems and often part of regulatory circuits rather than accidental events.DNA alterations are particu...

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Bibliographic Details
Main Authors: Marco Giorgio, Ivan Gaetano Dellino, Valentina Gambino, Niccolo’ Roda, Pier Giuseppe Pelicci
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171931064X