In vitro and in vivo activities of ruthenium(II) phosphine/diimine/picolinate complexes (SCAR) against Mycobacterium tuberculosis.

In vitro and in vivo activities of ruthenium(II) phosphine/diimine/picolinate complexes (SCAR) against Mycobacterium tuberculosis.

Rifampicin, discovered more than 50 years ago, represents the last novel class of antibiotics introduced for the first-line treatment of tuberculosis. Drugs in this class form part of a 6-month regimen that is ineffective against MDR and XDR TB, and incompatible with many antiretroviral drugs. Inves...

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Bibliographic Details
Main Authors: Fernando R Pavan, Gustavo V Poelhsitz, Lucas V P da Cunha, Marilia I F Barbosa, Sergio R A Leite, Alzir A Batista, Sang H Cho, Scott G Franzblau, Mariana S de Camargo, Flávia A Resende, Eliana A Varanda, Clarice Q F Leite
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3665843?pdf=render

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http://europepmc.org/articles/PMC3665843?pdf=render

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