Astragalus membranaceus Inhibits Peritoneal Fibrosis via Monocyte Chemoattractant Protein (MCP)-1 and the Transforming Growth Factor-β1 (TGF-β1) Pathway in Rats Submitted to Peritoneal Dialysis

Astragalus membranaceus Inhibits Peritoneal Fibrosis via Monocyte Chemoattractant Protein (MCP)-1 and the Transforming Growth Factor-β1 (TGF-β1) Pathway in Rats Submitted to Peritoneal Dialysis

Inflammation and transforming growth factor-β1 (TGF-β1) contribute to the development of peritoneal fibrosis (PF), which is associated with peritoneal dialysis (PD). Astragalus membranaceus (Astragalus) has anti-inflammatory and anti-fibrotic effects in many diseases. The goal of this study was to d...

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Bibliographic Details
Main Authors: Zhenghong Li, Lu Zhang, Weiming He, Changle Zhu, Jinsong Yang, Meixiao Sheng
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:International Journal of Molecular Sciences
Subjects:
Astragalus membranaceus
monocyte chemoattractant protein
transforming growth factor-β1
peritoneal fibrosis
peritoneal dialysis
Online Access:http://www.mdpi.com/1422-0067/15/7/12959

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http://www.mdpi.com/1422-0067/15/7/12959

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