20-hydroxyecdysone dilates muscle arterioles in a nitric oxide-dependent, estrogen ER-β receptor-independent manner

Background: 20-hydroxyecdysone is an ecdysteroid which is abundant in plants and insects and has anabolic potentials in mammals. It was recently shown to have affinity for estrogen ER-β receptor, which could potentially make it vasodilatory. Yet this possibility has not been previously investigated....

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Main Authors: Nelson N Orie, Asmaa Raees, Maneera Y. Aljaber, Nada Mohamed-Ali, Halima Bensmail, Mostafa M. Hamza, Nasser Al-Ansari, Alka Beotra, Vidya Mohamed-Ali, Mohammed Almaadheed
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Phytomedicine Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031321000609