Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish

The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix Salvia miltiorrhiza, namely tanshinone IIA (TIIA), cryptotanshinone (Cry) and tanshinone I (TI) were selected as model compounds, and their met...

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Bibliographic Details
Main Authors: Bing Wang, Xiaobin Jia, Luan Shu, Yunru Peng, Changmei Wang, Ping Li, Yingjie Wei, Wenquan Ma
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/7/8617