Independent regulation of basal neurotransmitter release efficacy by variable Ca²+ influx and bouton size at small central synapses.

The efficacy of action potential evoked neurotransmitter release varies widely even among synapses supplied by the same axon, and the number of release-ready vesicles at each synapse is a major determinant of this heterogeneity. Here we identify a second, equally important, mechanism for release het...

Full description

Bibliographic Details
Main Authors: Yaroslav S Ermolyuk, Felicity G Alder, Christian Henneberger, Dmitri A Rusakov, Dimitri M Kullmann, Kirill E Volynski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23049481/pdf/?tool=EBI