Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines.

Expression of the protease sensing receptor, protease activated receptor-2 (PAR2), is elevated in a variety of cancers and has been promoted as a potential therapeutic target. With the development of potent antagonists for this receptor, we hypothesised that they could be used to treat renal cell ca...

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Bibliographic Details
Main Authors: Christudas Morais, Retnagowri Rajandram, Jade S Blakeney, Abishek Iyer, Jacky Y Suen, David W Johnson, Glenda C Gobe, David P Fairlie, David A Vesey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0248983