A Phase II Study of Flavopiridol in Patients With Previously Untreated Advanced Soft Tissue Sarcoma

Purpose. Flavopiridol is a potent cyclin-dependent kinase (CDK) inhibitor that has preclinical activity in many tumours. This synthetic flavonoid was tested in a phase II nonrandomized, nonblinded multicentre clinical trial to determine its activity and toxicity in patients with previously untreated...

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Bibliographic Details
Main Authors: Don G. Morris, Vivien H. C. Bramwell, Robert Turcotte, Alvaro T. Figueredo, Martin E. Blackstein, Shail Verma, Sarah Matthews, Elizabeth A. Eisenhauer
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/SRCM/2006/64374