Herbal compound 861 prevents hepatic fibrosis by inhibiting the TGF-β1/Smad/SnoN pathway in bile duct-ligated rats

Abstract Background This study was to evaluate the effects of herbal compound 861 (Cpd861) on ski-related novel protein N (SnoN) and transforming growth factor-β1 (TGF-β1) /Smad signaling in rats with bile duct ligation (BDL)-induced hepatic fibrosis, and to explore the mechanisms of Cpd861 on hepat...

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Bibliographic Details
Main Authors: Cheng Chi, Xiao-ya Liu, Fei Hou, Xiao-zheng Yu, Chun-yun Li, Li-jian Cui, Rui-xia Liu, Cheng-hong Yin
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12906-018-2119-7