Targeting Smyd3 by next-generation antisense oligonucleotides suppresses liver tumor growth

Targeting Smyd3 by next-generation antisense oligonucleotides suppresses liver tumor growth

Summary: The oncogenic function of suppressor of variegation, enhancer of zeste and MYeloid-Nervy-DEAF1-domain family methyltransferase Smyd3 has been implicated in various malignancies, including hepatocellular carcinoma (HCC). Here, we show that targeting Smyd3 by next-generation antisense oligonu...

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Bibliographic Details
Main Authors: Haroula Kontaki, Marina Koukaki, Maria Vasilarou, Antonis Giakountis, Elena Deligianni, Xiaolin Luo, Youngsoo Kim, Iannis Talianidis
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Cancer
Epigenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221004417

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221004417

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