Functional Live-Cell Imaging Demonstrates that β-Integrin Promotes Type IV Collagen Degradation by Breast and Prostate Cancer Cells

The ability of tumor cells to adhere to, migrate on, and remodel extracellular matrices is mediated by cell surface receptors such as β 1 -integrins. Here we conducted functional live-cell imaging in real time to investigate the effects of modulating β 1 -integrin expression and function on proteoly...

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Bibliographic Details
Main Authors: Mansoureh Sameni, Julie Dosescu, Kenneth M. Yamada, Bonnie F. Sloane, Dora Cavallo-Medved
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2008-09-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2008.00019A