Functional Live-Cell Imaging Demonstrates that β-Integrin Promotes Type IV Collagen Degradation by Breast and Prostate Cancer Cells
The ability of tumor cells to adhere to, migrate on, and remodel extracellular matrices is mediated by cell surface receptors such as β 1 -integrins. Here we conducted functional live-cell imaging in real time to investigate the effects of modulating β 1 -integrin expression and function on proteoly...
Main Authors: | Mansoureh Sameni, Julie Dosescu, Kenneth M. Yamada, Bonnie F. Sloane, Dora Cavallo-Medved |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2008-09-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2008.00019A |
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