Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice[S]

Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice[S]

The cftr knockout mouse model of cystic fibrosis (CF) shows intestinal obstruction; malabsorption and inflammation; and a fatty acid imbalance in intestinal mucosa. We performed a lipid mapping of colon sections from CF and control (WT) mice by cluster time of flight secondary-ion mass spectrometry...

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Bibliographic Details
Main Authors: Marc Brulet, Alexandre Seyer, Aleksander Edelman, Alain Brunelle, Janine Fritsch, Mario Ollero, Olivier Laprévote
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Journal of Lipid Research
Subjects:
time of flight secondary-ion mass spectrometry
mass spectrometry
K-mean
partitioning clustering
principal component analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520409939

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http://www.sciencedirect.com/science/article/pii/S0022227520409939

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