Duration of FOLFOX Adjuvant Chemotherapy in High-Risk Stage II and Stage III Colon Cancer With Deficient Mismatch Repair

Duration of FOLFOX Adjuvant Chemotherapy in High-Risk Stage II and Stage III Colon Cancer With Deficient Mismatch Repair

BackgroundWe evaluated the impact of 3 months of mFOLFOX6 adjuvant chemotherapy or surgery alone in comparison with 6 months of mFOLFOX6 on disease-free survival (DFS) in deficient mismatch repair (dMMR) colon cancer (CC) patients.MethodsThis retrospective study identified a cohort of patients with...

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Bibliographic Details
Main Authors: Huabin Hu, Zehua Wu, Chao Wang, Yan Huang, Jianwei Zhang, Yue Cai, Xiaoyu Xie, Jianxia Li, Cailu Shen, Weiwei Li, Jiayu Ling, Xuehu Xu, Yanhong Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
colon cancer
adjuvant chemotherapy
deficient mismatch repair
microsatellite instability
duration of therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.579478/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.579478/full

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