Systemic expression of Alu RNA in patients with geographic atrophy secondary to age-related macular degeneration.

Systemic expression of Alu RNA in patients with geographic atrophy secondary to age-related macular degeneration.

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is characterized by irreversible loss of macular retinal tissue and retinal pigment epithelium (RPE) cells. Several studies have revealed that accumulation of Alu RNA in RPE cell causes RPE cell degeneration in AMD. In the p...

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Bibliographic Details
Main Authors: Hiroyuki Yoshida, Tokiyoshi Matsushita, Erika Kimura, Yukie Fujita, Robert Keany, Toshihiro Ikeda, Masanao Toshimori, Takahiro Imanaka, Masatsugu Nakamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220887

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https://doi.org/10.1371/journal.pone.0220887

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