The Interplay between Mucosal Microbiota Composition and Host Gene-Expression is Linked with Infliximab Response in Inflammatory Bowel Diseases

The Interplay between Mucosal Microbiota Composition and Host Gene-Expression is Linked with Infliximab Response in Inflammatory Bowel Diseases

Even though anti-TNF therapy significantly improves the rates of remission in inflammatory bowel disease (IBD) patients, there is a noticeable subgroup of patients who do not respond to treatment. Dysbiosis emerges as a key factor in IBD pathogenesis. The aim of the present study is to profile chang...

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Bibliographic Details
Main Authors: Nikolas Dovrolis, George Michalopoulos, George E. Theodoropoulos, Kostantinos Arvanitidis, George Kolios, Leonardo A. Sechi, Aristidis G. Eliopoulos, Maria Gazouli
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Microorganisms
Subjects:
inflammatory bowel disease
infliximab
microbiota
microbiome
anti-tnf
response to therapy
host transcriptome
biomarkers
Online Access:https://www.mdpi.com/2076-2607/8/3/438

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https://www.mdpi.com/2076-2607/8/3/438

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