Glucocorticoid receptor: translocation from the cytoplasm to the nuclei, chromatin and intranuclear chaperone cycles
Glucocorticoid receptor (GR) is a ligand-dependent transcription factor, involved in the regulation of hundreds of genes. In the absence of any ligand, GR resides in the cytoplasm where it is sequestered in a multimeric chaperone complex consisting of hsp90, hsp70, p23, Hop, FKBP51, FKBP52, etc. As...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
2015-07-01
|
| Series: | Vavilovskij Žurnal Genetiki i Selekcii |
| Subjects: | |
| Online Access: | https://vavilov.elpub.ru/jour/article/view/405 |