VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function

VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function

Dysregulated mitochondrial function is associated with the pathology of a wide range of diseases including renal disease and cancer. Thus, investigating regulators of mitochondrial function is of particular interest. Previous work has shown that the von Hippel-Lindau tumor suppressor protein (pVHL)...

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Bibliographic Details
Main Authors: Thomas Briston, Jenna M. Stephen, Luke W. Thomas, Cinzia Esposito, Yuen-Li Chung, Saiful E. Syafruddin, Mark Turmaine, Lucas A. Maddalena, Basma Greef, Gyorgy Szabadkai, Patrick H. Maxwell, Sakari Vanharanta, Margaret Ashcroft
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Oncology
Subjects:
von Hippel-Lindau protein (pVHL)
hypoxia inducible factor
mitochondria
bioenergetics
metabolism
CHCHD4
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00388/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00388/full

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