Lymphangiosis carcinomatosa in squamous cell carcinomas of larynx and hypopharynx – value of conventional evaluation and additional immunohistochemical staining of D2-40

<p>Abstract</p> <p>Background</p> <p>Recent studies revealed a predictive value of lymphatic vessel invasion (L1) for the nodal metastasizing and poor prognosis in malignant tumors at different sites. The monoclonal antibody D2-40 (podoplanin) stains specifically endoth...

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Bibliographic Details
Main Authors: Puppe Bernhard, Haubitz Imme, Metzger Alexandra, Nowack Isabell, Scheich Matthias, Völker Hans-Ullrich, Hagen Rudolf, Müller-Hermelink Hans-Konrad, Völter Christiane
Format: Article
Language:English
Published: BMC 2009-03-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/7/1/25