Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1

Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1

Objectives: The aim of this study was to assess soluble CD30 (sCD30), a protein that colocalises with HIV-1 RNA and DNA in lymphoid cells and tissues, in cerebrospinal fluid (CSF) as a marker of HIV-1 infection in the central nervous system (CNS). Methods: This was a cross-sectional study using arch...

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Bibliographic Details
Main Authors: Michael J. Peluso, Cassandra Thanh, Cecilia A. Prator, Louise E. Hogan, Victor M. Arechiga, Sophie Stephenson, Philip J. Norris, Clara Di Germanio, Dietmar Fuchs, Henrik Zetterberg, Steven G. Deeks, Magnus Gisslén, Richard W. Price, Timothy J. Henrich
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Virus Eradication
Subjects:
HIV-1
reservoir
central nervous system (CNS)
cerebrospinal fluid (CSF)
CD30
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020300066

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http://www.sciencedirect.com/science/article/pii/S2055664020300066

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