Effect of population heterogenization on the reproducibility of mouse behavior: a multi-laboratory study.

In animal experiments, animals, husbandry and test procedures are traditionally standardized to maximize test sensitivity and minimize animal use, assuming that this will also guarantee reproducibility. However, by reducing within-experiment variation, standardization may limit inference to the spec...

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Bibliographic Details
Main Authors: S Helene Richter, Joseph P Garner, Benjamin Zipser, Lars Lewejohann, Norbert Sachser, Chadi Touma, Britta Schindler, Sabine Chourbaji, Christiane Brandwein, Peter Gass, Niek van Stipdonk, Johanneke van der Harst, Berry Spruijt, Vootele Võikar, David P Wolfer, Hanno Würbel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21305027/?tool=EBI