ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2

Objective: Acute administration of the main protein component of high-density lipoprotein, apolipoprotein A-I (ApoA-1), improves glucose uptake in skeletal muscle. The molecular mechanisms mediating this are not known, but in muscle cell cultures, ApoA-1 failed to increase glucose uptake when infect...

Full description

Bibliographic Details
Main Authors: Andreas Mæchel Fritzen, Joan Domingo-Espín, Anne-Marie Lundsgaard, Maximilian Kleinert, Ida Israelsen, Christian S. Carl, Trine S. Nicolaisen, Rasmus Kjøbsted, Jacob F. Jeppesen, Jørgen F.P. Wojtaszewski, Jens O. Lagerstedt, Bente Kiens
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820300211