Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice

Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice

The potential of nicotinamide (NAM) to prevent atherosclerosis has not yet been examined. This study investigated the effect of NAM supplementation on the development of atherosclerosis in a mouse model of the disease. The development of aortic atherosclerosis was significantly reduced (NAM low dose...

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Bibliographic Details
Main Authors: Karen Alejandra Méndez-Lara, Nicole Letelier, Nuria Farre, Elena M. G. Diarte-Añazco, Núria Nieto-Nicolau, Elisabeth Rodríguez-Millán, David Santos, Victor Pallarès, Joan Carles Escolà-Gil, Tania Vázquez del Olmo, Enrique Lerma, Mercedes Camacho, Ricardo P Casaroli-Marano, Annabel F. Valledor, Francisco Blanco-Vaca, Josep Julve
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
macrophage
cytokine
ATP-binding cassette (ABC) transporters
niacinamide
vitamin B3
cardiovascular disease
Online Access:https://www.mdpi.com/2076-3921/9/11/1162

Internet

https://www.mdpi.com/2076-3921/9/11/1162

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