A protein quality control pathway at the mitochondrial outer membrane

Maintaining the essential functions of mitochondria requires mechanisms to recognize and remove misfolded proteins. However, quality control (QC) pathways for misfolded mitochondrial proteins remain poorly defined. Here, we establish temperature-sensitive (ts-) peripheral mitochondrial outer membran...

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Bibliographic Details
Main Authors: Meredith B Metzger, Jessica L Scales, Mitchell F Dunklebarger, Jadranka Loncarek, Allan M Weissman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
UPS
MAD
Online Access:https://elifesciences.org/articles/51065