The effects of naloxone, diazepam, and quercetin on seizure and sedation in acute on chronic tramadol administration: an experimental study

Abstract Background Tramadol is a widely used synthetic opioid. Substantial research has previously focused on the neurological effects of this drug, while the efficacy of various treatments to reduce the associated side effects has not been well studied. This study aimed to evaluate the protective...

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Main Authors: Samaneh Nakhaee, Khadijeh Farrokhfall, Ebrahim Miri-Moghaddam, Mohsen Foadoddini, Masoumeh Askari, Alireza Amirabadizadeh, Jeffrey Brent, Bruno Megarbane, Omid Mehrpour
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Behavioral and Brain Functions
Subjects:
Online Access:https://doi.org/10.1186/s12993-021-00178-w