The rs738409 polymorphism of the PNPLA3 gene is associated with hepatic steatosis and fibrosis in Brazilian patients with chronic hepatitis C

The rs738409 polymorphism of the PNPLA3 gene is associated with hepatic steatosis and fibrosis in Brazilian patients with chronic hepatitis C

Abstract Background Prospective studies have shown that 80% of acute hepatitis C virus (HCV) cases progress to chronic infection; approximately 10-20% of patients with these conditions will develop liver cirrhosis within 2 to 3 decades, and 1-5% will develop liver cancer. Some studies have indicated...

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Bibliographic Details
Main Authors: Caroline Manchiero, Arielle Karen da Silva Nunes, Mariana Carvalheiro Magri, Bianca Peixoto Dantas, Celso Carmo Mazza, Antonio Alci Barone, Fátima Mitiko Tengan
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Infectious Diseases
Subjects:
Hepatitis C
PNPLA3
Steatosis
Fibrosis
Polymorphism rs738409
TM6SF2
Online Access:http://link.springer.com/article/10.1186/s12879-017-2887-6

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http://link.springer.com/article/10.1186/s12879-017-2887-6

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