Protein aggregation in neurodegenerative disease: the nucleolar connection

Protein- and sometimes RNA-containing aggregates are a hallmark of many age-related neurodegenerative diseases. Aggregate depositions can be cytoplasmic, nuclear and even extracellular. This article focuses on nuclear aggregation and the potential role of a specific compartment—the nucleolus, in the...

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Bibliographic Details
Main Author: Leena Latonen
Format: Article
Language:English
Published: AIMS Press 2015-07-01
Series:AIMS Molecular Science
Subjects:
Online Access:http://www.aimspress.com/Molecular/article/335/fulltext.html