Impact of Nitric Oxide Bioavailability on the Progressive Cerebral and Peripheral Circulatory Impairments During Aging and Alzheimer's Disease

Impact of Nitric Oxide Bioavailability on the Progressive Cerebral and Peripheral Circulatory Impairments During Aging and Alzheimer's Disease

Advanced aging, vascular dysfunction, and nitric oxide (NO) bioavailability are recognized risk factors for Alzheimer's disease (AD). However, the contribution of AD, per se, to this putative pathophysiological mechanism is still unclear. To better answer this point, we quantified cortical perf...

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Bibliographic Details
Main Authors: Massimo Venturelli, Anna Pedrinolla, Ilaria Boscolo Galazzo, Cristina Fonte, Nicola Smania, Stefano Tamburin, Ettore Muti, Lucia Crispoltoni, Annamaria Stabile, Alessandra Pistilli, Mario Rende, Francesca B. Pizzini, Federico Schena
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Physiology
Subjects:
circulation
aging
Alzheimer's disease
nitric oxide
vascular dysfunction
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00169/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00169/full

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