Genetic Targeting of GRP78 in the VMH Improves Obesity Independently of Food Intake
Recent data have demonstrated that the hypothalamic GRP78/BiP (glucose regulated protein 78 kDa/binding immunoglobulin protein) modulates brown adipose tissue (BAT) thermogenesis by acting downstream on AMP-activated protein kinase (AMPK). Herein, we aimed to investigate whether genetic over-express...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-07-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/9/7/357 |