Flagellin attenuates experimental sepsis in a macrophage-dependent manner
Abstract Background Sepsis is the leading cause of death among critically ill patients, and no specific therapeutic agent is currently approved for the treatment of sepsis. Methods We assessed the effects of flagellin administration on survival, bacterial burden, and tissue injury after sepsis. In a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-04-01
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| Series: | Critical Care |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13054-019-2408-7 |