PKCε and Allopregnanolone: functional cross-talk at the GABAA receptor level

PKCε and Allopregnanolone: functional cross-talk at the GABAA receptor level

Changes in GABAergic inhibition occur during physiological processes, during response to drugs and in various pathologies. These changes can be achieved through direct allosteric modifications at the γ-aminobutyric (GABA) type A (GABAA) receptor protein level, or by altering the synthesis, trafficki...

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Bibliographic Details
Main Authors: Giulia ePuja, Federica eRavazzini, Luca Franco Castelnovo, Valerio eMagnaghi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Neurosteroids
GABAA receptor
phosphorylation site
receptor traffiking
PKCepsilon
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00083/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00083/full

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